8WFJ

human glycine transporter 1 in complex with ALX-5407 in inward facing conformation

Summary for 8WFJ

• Entry DOI: 10.2210/pdb8wfj/pdb
• EMDB information: 37493
• Descriptor: Sodium- and chloride-dependent glycine transporter 1, ALX5407 (2 entities in total)
• Functional Keywords: glyt1, alx-5407, inward-open, membrane protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 72926.60

Authors

Wei, Y.,Zhao, Y. (deposition date: 2023-09-19, release date: 2024-04-03, Last modification date: 2024-04-17)

• Primary citation: Wei, Y.,Li, R.,Meng, Y.,Hu, T.,Zhao, J.,Gao, Y.,Bai, Q.,Li, N.,Zhao, Y.; Transport mechanism and pharmacology of the human GlyT1.; Cell, 187:1719-, 2024; PubMed: 38513663; DOI: 10.1016/j.cell.2024.02.026

Experimental method

ELECTRON MICROSCOPY (3.35 Å)