8WCR

Cryo-EM structure of nanodisc (PE:PS:PC) reconstituted GLIC at pH 4 in open state

Summary for 8WCR

Entry DOI	10.2210/pdb8wcr/pdb
EMDB information	37447
Descriptor	Proton-gated ion channel, CHLORIDE ION, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ... (4 entities in total)
Functional Keywords	pentameric ligand-gated ion channels, cis-loop, cryo-em, nanodisc, membrane protein
Biological source	Gloeobacter violaceus
Total number of polymer chains	5
Total formula weight	212154.26
Authors	Bharambe, N.,Li, Z.,Basak, S. (deposition date: 2023-09-13, release date: 2024-04-17)
Primary citation	Bharambe, N.,Li, Z.,Seiferth, D.,Balakrishna, A.M.,Biggin, P.C.,Basak, S. Cryo-EM structures of prokaryotic ligand-gated ion channel GLIC provide insights into gating in a lipid environment. Nat Commun, 15:2967-2967, 2024 Cited by PubMed: 38580666 DOI: 10.1038/s41467-024-47370-w PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.74 Å)

Structure validation