8WCC
Cryo-EM structure of the CHA-bound mTAAR1 complex
Summary for 8WCC
Entry DOI | 10.2210/pdb8wcc/pdb |
EMDB information | 37438 |
Descriptor | Trace amine-associated receptor 1, CYCLOHEXYLAMMONIUM ION (2 entities in total) |
Functional Keywords | cha, mtaar1, membrane protein |
Biological source | Mus musculus (house mouse) |
Total number of polymer chains | 1 |
Total formula weight | 37756.77 |
Authors | Rong, N.K.,Guo, L.L.,Zhang, M.H.,Li, Q.,Yang, F.,Sun, J.P. (deposition date: 2023-09-11, release date: 2023-12-27) |
Primary citation | Shang, P.,Rong, N.,Jiang, J.J.,Cheng, J.,Zhang, M.H.,Kang, D.,Qi, L.,Guo, L.,Yang, G.M.,Liu, Q.,Zhou, Z.,Li, X.B.,Zhu, K.K.,Meng, Q.B.,Han, X.,Yan, W.,Kong, Y.,Yang, L.,Wang, X.,Lei, D.,Feng, X.,Liu, X.,Yu, X.,Wang, Y.,Li, Q.,Shao, Z.H.,Yang, F.,Sun, J.P. Structural and signaling mechanisms of TAAR1 enabled preferential agonist design. Cell, 186:5347-5362.e24, 2023 Cited by PubMed: 37963465DOI: 10.1016/j.cell.2023.10.014 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.04 Å) |
Structure validation
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