8W7A

Cryo-EM structure of ClassIII Lanthipeptide modification enzyme PneKC in the presence of GTP.

Summary for 8W7A

• Entry DOI: 10.2210/pdb8w7a/pdb
• EMDB information: 37337
• Descriptor: Protein kinase domain-containing protein, GUANOSINE-5'-TRIPHOSPHATE (2 entities in total)
• Functional Keywords: lanthibiotic, ripps, lankc, cryoem, antimicrobial peptides, antiviral peptides., antimicrobial protein
• Biological source: Streptococcus pneumoniae
• Total number of polymer chains: 2
• Total formula weight: 200866.68

Authors

Li, Y.,Luo, M.,Shao, K.,Li, J. (deposition date: 2023-08-30, release date: 2024-08-28)

• Primary citation: Li, Y.,Shao, K.,Li, Z.,Zhu, K.,Gan, B.K.,Shi, J.,Xiao, Y.,Luo, M.; Mechanistic insights into lanthipeptide modification by a distinct subclass of LanKC enzyme that forms dimers.; Nat Commun, 15:7090-7090, 2024; PubMed: 39154050; DOI: 10.1038/s41467-024-51600-6

Experimental method

ELECTRON MICROSCOPY (3.77 Å)