8W0Q
Pembrolizumab CDR-H3 Loop Mimic
Summary for 8W0Q
| Entry DOI | 10.2210/pdb8w0q/pdb |
| NMR Information | BMRB: 31146 |
| Descriptor | Pembrolizumab CDR-H3 Loop Mimic (1 entity in total) |
| Functional Keywords | cdr-h3 loop, antibody, bulged hairpin, conformational ensemble, beta-hairpin, peptide mimic, immune system |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 1 |
| Total formula weight | 2667.96 |
| Authors | Feig, M.,Roche, S.P. (deposition date: 2024-02-14, release date: 2024-07-03, Last modification date: 2024-07-10) |
| Primary citation | Zhao, G.,Richaud, A.D.,Williamson, R.T.,Feig, M.,Roche, S.P. De Novo Synthesis and Structural Elucidation of CDR-H3 Loop Mimics. Acs Chem.Biol., 2024 Cited by PubMed: 38916527DOI: 10.1021/acschembio.4c00236 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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