8W0N
IRED crystal structure
Summary for 8W0N
Entry DOI | 10.2210/pdb8w0n/pdb |
Descriptor | IRED, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, DIMETHYL SULFOXIDE, ... (6 entities in total) |
Functional Keywords | protein engineering, imine reductase, scalable manufacturing, oxidoreductase |
Biological source | Bacillus subtilis |
Total number of polymer chains | 2 |
Total formula weight | 57744.06 |
Authors | |
Primary citation | Yi, X.,Kleinbeck, F.,Ching, C.,Boghospor, L.,Gomes, S.,Alvizo, O.,Allmendinger, T.,Fell, J.,Subramanian, N.,Li, M.,Garcia, R.,Riggins, J.,Entwistle, D.,Richter, Y.,Gschwend, D.,Lauener, L.,Peat, T.S.,Lebhar, H.,Schlama, T.,Ruch, T. Enhancing the Imine Reductase Activity of a Promiscuous Glucose Dehydrogenase for Scalable Manufacturing of a Chiral Neprilysin Inhibitor Precursor Acs Catalysis, 14:7087-7096, 2024 Cited by DOI: 10.1021/acscatal.3c05615PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.37 Å) |
Structure validation
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