8W0N

IRED crystal structure

8W0N の概要

• エントリーDOI: 10.2210/pdb8w0n/pdb
• 分子名称: IRED, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, DIMETHYL SULFOXIDE, ... (6 entities in total)
• 機能のキーワード: protein engineering, imine reductase, scalable manufacturing, oxidoreductase
• 由来する生物種: Bacillus subtilis
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 57744.06

構造登録者

Peat, T.S.,Newman, J. (登録日: 2024-02-13, 公開日: 2024-07-24)

• 主引用文献: Yi, X.,Kleinbeck, F.,Ching, C.,Boghospor, L.,Gomes, S.,Alvizo, O.,Allmendinger, T.,Fell, J.,Subramanian, N.,Li, M.,Garcia, R.,Riggins, J.,Entwistle, D.,Richter, Y.,Gschwend, D.,Lauener, L.,Peat, T.S.,Lebhar, H.,Schlama, T.,Ruch, T.; Enhancing the Imine Reductase Activity of a Promiscuous Glucose Dehydrogenase for Scalable Manufacturing of a Chiral Neprilysin Inhibitor Precursor; Acs Catalysis, 14:7087-7096, 2024; DOI: 10.1021/acscatal.3c05615

実験手法

X-RAY DIFFRACTION (1.37 Å)