Summary for 8VZV
Entry DOI | 10.2210/pdb8vzv/pdb |
Related | 7LU7 |
Descriptor | Tryptophan 2,3-dioxygenase, PROTOPORPHYRIN IX CONTAINING FE, alpha-methyl-L-tryptophan, ... (5 entities in total) |
Functional Keywords | human tdo, htdo, lm10, cytosolic protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 184756.74 |
Authors | Ishigami, I.,Yeh, S.-R.,Lewis-Ballester, A. (deposition date: 2024-02-12, release date: 2024-08-28, Last modification date: 2024-09-11) |
Primary citation | Geeraerts, Z.,Ishigami, I.,Lewis-Ballester, A.,Pham, K.N.,Kozlova, A.,Mathieu, C.,Frederick, R.,Yeh, S.R. Structural Insights into Protein-Inhibitor Interactions in Human Tryptophan Dioxygenase. J.Med.Chem., 67:14543-14552, 2024 Cited by PubMed: 39106326DOI: 10.1021/acs.jmedchem.4c01360 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.29 Å) |
Structure validation
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