8VY4
Engineering a Tumor-Selective Prodrug T Cell Engager Bispecific Antibody for Safer Immunotherapy
Summary for 8VY4
Entry DOI | 10.2210/pdb8vy4/pdb |
Descriptor | Fab Heavy Chain, Fab Light Chain, PCA-ASP-GLY-ASN-GLU-GLU-MET, ... (4 entities in total) |
Functional Keywords | antibody, cd3, immune system |
Biological source | Mus musculus More |
Total number of polymer chains | 3 |
Total formula weight | 47675.87 |
Authors | Antonysamy, S.,Demarest, S.,Froning, K.,Hickey, M.H.,Kuhlman, B.,McCue, A.C. (deposition date: 2024-02-06, release date: 2024-07-24) |
Primary citation | McCue, A.C.,Demarest, S.J.,Froning, K.J.,Hickey, M.J.,Antonysamy, S.,Kuhlman, B. Engineering a tumor-selective prodrug T-cell engager bispecific antibody for safer immunotherapy. Mabs, 16:2373325-2373325, 2024 Cited by PubMed: 38962811DOI: 10.1080/19420862.2024.2373325 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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