8VY4

Engineering a Tumor-Selective Prodrug T Cell Engager Bispecific Antibody for Safer Immunotherapy

8VY4 の概要

• エントリーDOI: 10.2210/pdb8vy4/pdb
• 分子名称: Fab Heavy Chain, Fab Light Chain, PCA-ASP-GLY-ASN-GLU-GLU-MET, ... (4 entities in total)
• 機能のキーワード: antibody, cd3, immune system
• 由来する生物種: Mus musculus; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 47675.87

構造登録者

Antonysamy, S.,Demarest, S.,Froning, K.,Hickey, M.H.,Kuhlman, B.,McCue, A.C. (登録日: 2024-02-06, 公開日: 2024-07-24)

• 主引用文献: McCue, A.C.,Demarest, S.J.,Froning, K.J.,Hickey, M.J.,Antonysamy, S.,Kuhlman, B.; Engineering a tumor-selective prodrug T-cell engager bispecific antibody for safer immunotherapy.; Mabs, 16:2373325-2373325, 2024; PubMed: 38962811; DOI: 10.1080/19420862.2024.2373325

実験手法

X-RAY DIFFRACTION (1.7 Å)