8VTB

SthK R120A R124A in the presence of PIP2 and cAMP

Summary for 8VTB

Entry DOI	10.2210/pdb8vtb/pdb
EMDB information	43522
Descriptor	Transcriptional regulator, Crp/Fnr family, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE (3 entities in total)
Functional Keywords	cyclic-nucleotide binding, potassium channel, lipid modulation, transport protein
Biological source	Spirochaeta thermophila
Total number of polymer chains	4
Total formula weight	222563.40
Authors	Schmidpeter, P.A.M.,Thon, O.,Nimigean, C.M. (deposition date: 2024-01-26, release date: 2024-09-25, Last modification date: 2024-10-02)
Primary citation	Thon, O.,Wang, Z.,Schmidpeter, P.A.M.,Nimigean, C.M. PIP2 inhibits pore opening of the cyclic nucleotide-gated channel SthK. Nat Commun, 15:8230-8230, 2024 Cited by PubMed: 39300080 DOI: 10.1038/s41467-024-52469-1 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.5 Å)

Structure validation