8VT2

cryo-EM structure of HMPV (MPV-2c)

This is a non-PDB format compatible entry.

Summary for 8VT2

• Entry DOI: 10.2210/pdb8vt2/pdb
• EMDB information: 43516
• Descriptor: Prefusion of HMPV (MPV-2c), beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: prefusion, hmpv, cryo-em, virus, viral protein
• Biological source: Human metapneumovirus
• Total number of polymer chains: 3
• Total formula weight: 173357.21

Authors

Yu, X.,Langedijk, J.P.M. (deposition date: 2024-01-25, release date: 2024-07-31, Last modification date: 2024-08-07)

• Primary citation: Bakkers, M.J.G.,Ritschel, T.,Tiemessen, M.,Dijkman, J.,Zuffiano, A.A.,Yu, X.,van Overveld, D.,Le, L.,Voorzaat, R.,van Haaren, M.M.,de Man, M.,Tamara, S.,van der Fits, L.,Zahn, R.,Juraszek, J.,Langedijk, J.P.M.; Efficacious human metapneumovirus vaccine based on AI-guided engineering of a closed prefusion trimer.; Nat Commun, 15:6270-6270, 2024; PubMed: 39054318; DOI: 10.1038/s41467-024-50659-5

Experimental method

ELECTRON MICROSCOPY (3.14 Å)