8VSC
L-TGF-b1/GARP
Summary for 8VSC
| Entry DOI | 10.2210/pdb8vsc/pdb |
| EMDB information | 43489 43492 43493 |
| Descriptor | Transforming growth factor beta-1 proprotein, Transforming growth factor beta activator LRRC32 (2 entities in total) |
| Functional Keywords | tgfb, complex, signaling protein |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 3 |
| Total formula weight | 154854.48 |
| Authors | Jin, M.,Cheng, Y.,Nishimura, S.L. (deposition date: 2024-01-23, release date: 2024-09-11, Last modification date: 2024-10-02) |
| Primary citation | Jin, M.,Seed, R.I.,Cai, G.,Shing, T.,Wang, L.,Ito, S.,Cormier, A.,Wankowicz, S.A.,Jespersen, J.M.,Baron, J.L.,Carey, N.D.,Campbell, M.G.,Yu, Z.,Tang, P.K.,Cossio, P.,Wen, W.,Lou, J.,Marks, J.,Nishimura, S.L.,Cheng, Y. Dynamic allostery drives autocrine and paracrine TGF-beta signaling. Cell, 2024 Cited by PubMed: 39288764DOI: 10.1016/j.cell.2024.08.036 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (3 Å) |
Structure validation
Download full validation report
