8VSC
L-TGF-b1/GARP
Summary for 8VSC
Entry DOI | 10.2210/pdb8vsc/pdb |
EMDB information | 43489 43492 43493 |
Descriptor | Transforming growth factor beta-1 proprotein, Transforming growth factor beta activator LRRC32 (2 entities in total) |
Functional Keywords | tgfb, complex, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 154854.48 |
Authors | Jin, M.,Cheng, Y.,Nishimura, S.L. (deposition date: 2024-01-23, release date: 2024-09-11, Last modification date: 2024-10-02) |
Primary citation | Jin, M.,Seed, R.I.,Cai, G.,Shing, T.,Wang, L.,Ito, S.,Cormier, A.,Wankowicz, S.A.,Jespersen, J.M.,Baron, J.L.,Carey, N.D.,Campbell, M.G.,Yu, Z.,Tang, P.K.,Cossio, P.,Wen, W.,Lou, J.,Marks, J.,Nishimura, S.L.,Cheng, Y. Dynamic allostery drives autocrine and paracrine TGF-beta signaling. Cell, 2024 Cited by PubMed: 39288764DOI: 10.1016/j.cell.2024.08.036 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3 Å) |
Structure validation
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