8VRE
Structure of PYCR1 complexed with NADH and N-formyl-L-proline
Summary for 8VRE
Entry DOI | 10.2210/pdb8vre/pdb |
Descriptor | Pyrroline-5-carboxylate reductase 1, mitochondrial, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 1-formyl-L-proline, ... (5 entities in total) |
Functional Keywords | amino-acid biosynthesis, oxidoreductase, proline biosynthesis |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 5 |
Total formula weight | 171897.91 |
Authors | |
Primary citation | Meeks, K.R.,Bogner, A.N.,Tanner, J.J. Screening a knowledge-based library of low molecular weight compounds against the proline biosynthetic enzyme 1-pyrroline-5-carboxylate 1 (PYCR1) Protein Sci., 33:-, 2024 Cited by DOI: 10.1002/pro.5072PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.83 Å) |
Structure validation
Download full validation report