8VQC

Structure of the voltage-gated sodium channel NavPas from American Cockroach Periplaneta Americana in complex with scorpion alpha-toxin LqhaIT

Summary for 8VQC

Entry DOI	10.2210/pdb8vqc/pdb
EMDB information	43438
Descriptor	Sodium channel protein PaFPC1, Alpha-insect toxin LqhaIT, beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	navpas, scorpion toxin, ion channel, voltage-gated sodium channel, membrane protein
Biological source	Periplaneta americana (American cockroach) More
Total number of polymer chains	2
Total formula weight	194647.00
Authors	Phulera, S.,Khoshouei, M.,Whicher, J.,Weihofen, W.A. (deposition date: 2024-01-18, release date: 2024-09-04)
Primary citation	Phulera, S.,Dickson, C.J.,Schwalen, C.J.,Khoshouei, M.,Cassell, S.J.,Sun, Y.,Condos, T.,Whicher, J.,Weihofen, W.A. Scorpion alpha-toxin Lqh alpha IT specifically interacts with a glycan at the pore domain of voltage-gated sodium channels. Structure, 2024 Cited by PubMed: 39181123 DOI: 10.1016/j.str.2024.07.021 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.9 Å)

Structure validation