8VQB

Prefusion stabilized structure of the SARS-CoV-2 fusion machinery

Summary for 8VQB

Entry DOI	10.2210/pdb8vqb/pdb
EMDB information	43437
Descriptor	Spike protein S2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywords	sarbecoviruses, spike glycoprotein, fusion protein, prefusion-stabilized, seattle structural genomics center for infectious disease, ssgcid, viral protein
Biological source	Sarbecovirus
Total number of polymer chains	3
Total formula weight	211336.04
Authors	Lee, J.,Veesler, D.,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2024-01-18, release date: 2024-07-24)
Primary citation	Lee, J.,Stewart, C.,Schafer, A.,Leaf, E.M.,Park, Y.J.,Asarnow, D.,Powers, J.M.,Treichel, C.,Sprouse, K.R.,Corti, D.,Baric, R.,King, N.P.,Veesler, D. A broadly generalizable stabilization strategy for sarbecovirus fusion machinery vaccines. Nat Commun, 15:5496-5496, 2024 Cited by PubMed: 38944664 DOI: 10.1038/s41467-024-49656-5 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3 Å)

Structure validation