8VPH

CamA Adenine Methyltransferase Complexed to Cognate Substrate DNA and Containing Quinoline-based SGI-1027 Analog 455 and Inhibitor MC4741

これはPDB形式変換不可エントリーです。

8VPH の概要

• エントリーDOI: 10.2210/pdb8vph/pdb
• 分子名称: Site-specific DNA-methyltransferase (adenine-specific), DNA Strand II, DNA Strand I, ... (6 entities in total)
• 機能のキーワード: dna adenine methylation, protein-dna complex, transferase, dna binding protein, dna binding protein-dna complex, dna binding protein/dna
• 由来する生物種: Clostridioides difficile; 詳細
• タンパク質・核酸の鎖数: 9
• 化学式量合計: 233597.79

構造登録者

Zhou, J.,Horton, J.R.,Cheng, X. (登録日: 2024-01-16, 公開日: 2024-09-25)

• 主引用文献: Zhou, J.,Chen, Q.,Ren, R.,Yang, J.,Chang, C.,Liu, B.,Horton, J.R.,Li, C.,Maksoud, L.,Yang, Y.,Rotili, D.,Jain, A.K.,Zhang, X.,Blumenthal, R.M.,Chen, T.,Gao, Y.,Valente, S.,Mai, A.,Cheng, X.; Quinoline-based compounds can inhibit diverse enzymes that act on DNA; Cell Chem Biol, 2024

実験手法

X-RAY DIFFRACTION (3.18 Å)