8VL0

The crystal structure of wild-type CYP199A4 bound to 4-(2-oxopropyl)benzoic acid

Summary for 8VL0

Entry DOI	10.2210/pdb8vl0/pdb
Descriptor	Cytochrome P450, 4-(2-oxopropyl)benzoic acid, PROTOPORPHYRIN IX CONTAINING FE, ... (5 entities in total)
Functional Keywords	cytochrome p450, 4-(2-oxopropyl)benzoic acid, oxidoreductase
Biological source	Rhodopseudomonas palustris HaA2
Total number of polymer chains	1
Total formula weight	45417.56
Authors	Podgorski, M.N.,Bell, S.G. (deposition date: 2024-01-11, release date: 2024-05-08, Last modification date: 2024-07-31)
Primary citation	Lee, J.H.Z.,Coleman, T.,Mclean, M.A.,Podgorski, M.N.,Hayball, E.F.,Stone, I.S.J.,Bruning, J.B.,Whelan, F.,De Voss, J.J.,Sligar, S.G.,Bell, S.G. Selective alpha-Hydroxyketone Formation and Subsequent C-C Bond Cleavage by Cytochrome P450 Monooxygenase Enzymes Acs Catalysis, 14:8958-8971, 2024 Cited by DOI: 10.1021/acscatal.4c01766 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.837 Å)

Structure validation