8VL0

The crystal structure of wild-type CYP199A4 bound to 4-(2-oxopropyl)benzoic acid

8VL0 の概要

• エントリーDOI: 10.2210/pdb8vl0/pdb
• 分子名称: Cytochrome P450, 4-(2-oxopropyl)benzoic acid, PROTOPORPHYRIN IX CONTAINING FE, ... (5 entities in total)
• 機能のキーワード: cytochrome p450, 4-(2-oxopropyl)benzoic acid, oxidoreductase
• 由来する生物種: Rhodopseudomonas palustris HaA2
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 45417.56

構造登録者

Podgorski, M.N.,Bell, S.G. (登録日: 2024-01-11, 公開日: 2024-05-08, 最終更新日: 2024-07-31)

• 主引用文献: Lee, J.H.Z.,Coleman, T.,Mclean, M.A.,Podgorski, M.N.,Hayball, E.F.,Stone, I.S.J.,Bruning, J.B.,Whelan, F.,De Voss, J.J.,Sligar, S.G.,Bell, S.G.; Selective alpha-Hydroxyketone Formation and Subsequent C-C Bond Cleavage by Cytochrome P450 Monooxygenase Enzymes; Acs Catalysis, 14:8958-8971, 2024; DOI: 10.1021/acscatal.4c01766

実験手法

X-RAY DIFFRACTION (1.837 Å)