8VKU
Structure of VCP in complex with an ATPase activator (D2 domains only, hexameric form)
This is a non-PDB format compatible entry.
Summary for 8VKU
Entry DOI | 10.2210/pdb8vku/pdb |
EMDB information | 43329 43343 43392 |
Descriptor | Transitional endoplasmic reticulum ATPase, (3R)-N-[2-(ethylsulfanyl)phenyl]-3-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)butanamide (2 entities in total) |
Functional Keywords | activator, complex, atpase, aaa protein, hydrolase, hydrolase-activator complex, hydrolase/activator |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 6 |
Total formula weight | 538747.72 |
Authors | |
Primary citation | Jones, N.H.,Liu, Q.,Urnavicius, L.,Dahan, N.E.,Vostal, L.E.,Kapoor, T.M. Allosteric activation of VCP, an AAA unfoldase, by small molecule mimicry. Proc.Natl.Acad.Sci.USA, 121:e2316892121-e2316892121, 2024 Cited by PubMed: 38833472DOI: 10.1073/pnas.2316892121 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.5 Å) |
Structure validation
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