8VK2

X-ray crystal structure of human IgE 4C8 Fab

Summary for 8VK2

• Entry DOI: 10.2210/pdb8vk2/pdb
• Descriptor: IgE 4C8 light chain, IgE 4C8 heavy chain (3 entities in total)
• Functional Keywords: ige antibody, human immune system, human ige antibody, anti der p 2 antibody, ige against dust mite, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 93874.21

Authors

Khatri, K.,Ball, A.,Smith, S.A.,Champan, M.D.,Pomes, A.,Chruszcz, M. (deposition date: 2024-01-08, release date: 2024-06-19)

• Primary citation: Ball, A.,Khatri, K.,Glesner, J.,Vailes, L.D.,Wunschmann, S.,Gabel, S.A.,Mueller, G.A.,Zhang, J.,Peebles Jr., R.S.,Chapman, M.D.,Smith, S.A.,Chruszcz, M.,Pomes, A.; Structural analysis of human IgE monoclonal antibody epitopes on dust mite allergen Der p 2.; J.Allergy Clin.Immunol., 2024; PubMed: 38697404; DOI: 10.1016/j.jaci.2024.04.017

Experimental method

X-RAY DIFFRACTION (2.508 Å)