8VH7

Crystal structure of heparosan synthase 2 from Pasteurella multocida at 1.98 A

Summary for 8VH7

Entry DOI	10.2210/pdb8vh7/pdb
Descriptor	Heparosan synthase B, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE, ... (6 entities in total)
Functional Keywords	glycosyltransferase, heparosan, chemoenzymatic synthesis, heparan sulfate, transferase
Biological source	Pasteurella multocida
Total number of polymer chains	2
Total formula weight	130001.55
Authors	Pedersen, L.C.,Liu, J.,Stancanelli, E.,Krahn, J.M. (deposition date: 2023-12-31, release date: 2024-07-24)
Primary citation	Stancanelli, E.,Krahn, J.A.,Viverette, E.,Dutcher, R.,Pagadala, V.,Borgnia, M.J.,Liu, J.,Pedersen, L.C. Structural and Functional Analysis of Heparosan Synthase 2 from Pasteurella multocida to Improve the Synthesis of Heparin Acs Catalysis, 14:6577-6588, 2024 Cited by DOI: 10.1021/acscatal.4c00677 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.982 Å)

Structure validation