8VH7

Crystal structure of heparosan synthase 2 from Pasteurella multocida at 1.98 A

8VH7 の概要

• エントリーDOI: 10.2210/pdb8vh7/pdb
• 分子名称: Heparosan synthase B, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE, ... (6 entities in total)
• 機能のキーワード: glycosyltransferase, heparosan, chemoenzymatic synthesis, heparan sulfate, transferase
• 由来する生物種: Pasteurella multocida
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 130001.55

構造登録者

Pedersen, L.C.,Liu, J.,Stancanelli, E.,Krahn, J.M. (登録日: 2023-12-31, 公開日: 2024-07-24)

• 主引用文献: Stancanelli, E.,Krahn, J.A.,Viverette, E.,Dutcher, R.,Pagadala, V.,Borgnia, M.J.,Liu, J.,Pedersen, L.C.; Structural and Functional Analysis of Heparosan Synthase 2 from Pasteurella multocida to Improve the Synthesis of Heparin; Acs Catalysis, 14:6577-6588, 2024; DOI: 10.1021/acscatal.4c00677

実験手法

X-RAY DIFFRACTION (1.982 Å)