8VFY

Cryo-EM structure of FoxA1 in complex with ALBN1 nucleosome (class 1)

Summary for 8VFY

• Entry DOI: 10.2210/pdb8vfy/pdb
• EMDB information: 43194
• Descriptor: Histone H3.1, Histone H4, Histone H2A type 1-B/E, ... (7 entities in total)
• Functional Keywords: nucleosome, pioneer transcription factors, dna binding proteins, transcription, chromatin, nuclear protein, nuclear protein-dna complex, nuclear protein/dna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 11
• Total formula weight: 274714.73

Authors

Zhou, B.R.,Bai, Y. (deposition date: 2023-12-22, release date: 2024-08-07, Last modification date: 2024-09-11)

• Primary citation: Zhou, B.R.,Feng, H.,Huang, F.,Zhu, I.,Portillo-Ledesma, S.,Shi, D.,Zaret, K.S.,Schlick, T.,Landsman, D.,Wang, Q.,Bai, Y.; Structural insights into the cooperative nucleosome recognition and chromatin opening by FOXA1 and GATA4.; Mol.Cell, 84:3061-, 2024; PubMed: 39121853; DOI: 10.1016/j.molcel.2024.07.016

Experimental method

ELECTRON MICROSCOPY (2.89 Å)