8VAX
Cadmium catalyzed primer extension product with 14mer primer and mixed phosphorothioate activated G monomer
This is a non-PDB format compatible entry.
Summary for 8VAX
Entry DOI | 10.2210/pdb8vax/pdb |
Descriptor | Cadmium catalyzed nonenzymatic RNA primer extension product, MAGNESIUM ION, 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, ... (4 entities in total) |
Functional Keywords | phosphorothioate, cadmium, thiophilic metal ion, nonenzymatic primer extension, rna |
Biological source | synthetic construct |
Total number of polymer chains | 2 |
Total formula weight | 10564.12 |
Authors | Fang, Z.,Szostak, J.W. (deposition date: 2023-12-11, release date: 2024-04-17, Last modification date: 2024-05-01) |
Primary citation | Fang, Z.,Pazienza, L.T.,Zhang, J.,Tam, C.P.,Szostak, J.W. Catalytic Metal Ion-Substrate Coordination during Nonenzymatic RNA Primer Extension. J.Am.Chem.Soc., 146:10632-10639, 2024 Cited by PubMed: 38579124DOI: 10.1021/jacs.4c00323 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.417 Å) |
Structure validation
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