8V3K

F95S-F198S epi-Isozizaene Synthase: complex with 3 Mg2+, inorganic pyrophosphate, and benzyl triethyl ammonium cation

8V3K の概要

• エントリーDOI: 10.2210/pdb8v3k/pdb
• 分子名称: Epi-isozizaene synthase, GLYCEROL, MAGNESIUM ION, ... (7 entities in total)
• 機能のキーワード: terpene, terpenoid, isoprenoid, cyclase, lyase
• 由来する生物種: Streptomyces coelicolor A3(2)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 44315.25

構造登録者

Christianson, D.W.,Eaton, S.A. (登録日: 2023-11-28, 公開日: 2024-01-24, 最終更新日: 2024-04-03)

• 主引用文献: Eaton, S.A.,Christianson, D.W.; Structure-Based Engineering of a Sesquiterpene Cyclase to Generate an Alcohol Product: Conversion of epi -Isozizaene Synthase into alpha-Bisabolol Synthase.; Biochemistry, 63:797-805, 2024; PubMed: 38420671; DOI: 10.1021/acs.biochem.3c00681

実験手法

X-RAY DIFFRACTION (1.47 Å)