8UTQ

KIF1A[1-393] AMP-PNP bound one-head-bound state in complex with a microtubule - class T1L02*

Summary for 8UTQ

Entry DOI	10.2210/pdb8utq/pdb
EMDB information	42546
Descriptor	Kinesin-like protein KIF1A, Tubulin alpha-1B chain, Tubulin beta-2B chain, ... (8 entities in total)
Functional Keywords	kif1a, kinesin, motility, microtubule, tubulin, motor protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	5
Total formula weight	253916.79
Authors	Benoit, M.P.M.H.,Rao, L.,Asenjo, A.B.,Gennerich, A.,Sosa, H. (deposition date: 2023-10-31, release date: 2024-06-12, Last modification date: 2024-07-31)
Primary citation	Benoit, M.P.M.H.,Rao, L.,Asenjo, A.B.,Gennerich, A.,Sosa, H. Cryo-EM unveils kinesin KIF1A's processivity mechanism and the impact of its pathogenic variant P305L. Nat Commun, 15:5530-5530, 2024 Cited by PubMed: 38956021 DOI: 10.1038/s41467-024-48720-4 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.1 Å)

Structure validation