8UT7

CryoEM structure of A/Perth/16/2009 H3 in complex with polyclonal Fab from mice immunized with H3 stem nanoparticles-28 days post immunization

8UT7 の概要

• エントリーDOI: 10.2210/pdb8ut7/pdb
• EMDBエントリー: 42532
• 分子名称: H3D28 pFab HC Fv_polyA, H3D28 pFab LC Fv_polyA, Hemagglutinin, ... (5 entities in total)
• 機能のキーワード: cryoempem, flu hemagglutinin, central stem epitope, vh1-18, viral protein, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Influenza A virus; 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 213223.64

構造登録者

Huang, J.,Han, J.,Ward, A.B. (登録日: 2023-10-30, 公開日: 2024-05-08, 最終更新日: 2024-05-29)

• 主引用文献: Ray, R.,Nait Mohamed, F.A.,Maurer, D.P.,Huang, J.,Alpay, B.A.,Ronsard, L.,Xie, Z.,Han, J.,Fernandez-Quintero, M.,Phan, Q.A.,Ursin, R.L.,Vu, M.,Kirsch, K.H.,Prum, T.,Rosado, V.C.,Bracamonte-Moreno, T.,Okonkwo, V.,Bals, J.,McCarthy, C.,Nair, U.,Kanekiyo, M.,Ward, A.B.,Schmidt, A.G.,Batista, F.D.,Lingwood, D.; Eliciting a single amino acid change by vaccination generates antibody protection against group 1 and group 2 influenza A viruses.; Immunity, 57:1141-1159.e11, 2024; PubMed: 38670113; DOI: 10.1016/j.immuni.2024.03.022

実験手法

ELECTRON MICROSCOPY (2.7 Å)