8UR7
I53_dn5 nanoparticle displaying the trimeric HA heads with heptad domain, TH-6heptad-I53_dn5 (local refinement of TH-6heptad)
Summary for 8UR7
Entry DOI | 10.2210/pdb8ur7/pdb |
EMDB information | 42486 |
Descriptor | Trimer head HA,Hemagglutinin HA1 chain, 2-acetamido-2-deoxy-beta-D-glucopyranose (2 entities in total) |
Functional Keywords | influenza virus, hemagglutinin nanoparticle vaccine, structural genomics, seattle structural genomics center for infectious disease, ssgcid, viral protein |
Biological source | synthetic construct More |
Total number of polymer chains | 3 |
Total formula weight | 147732.61 |
Authors | Park, Y.J.,Veesler, D.,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2023-10-25, release date: 2023-12-27) |
Primary citation | Ellis, D.,Dosey, A.,Boyoglu-Barnum, S.,Park, Y.J.,Gillespie, R.,Syeda, H.,Hutchinson, G.B.,Tsybovsky, Y.,Murphy, M.,Pettie, D.,Matheson, N.,Chan, S.,Ueda, G.,Fallas, J.A.,Carter, L.,Graham, B.S.,Veesler, D.,Kanekiyo, M.,King, N.P. Antigen spacing on protein nanoparticles influences antibody responses to vaccination. Cell Rep, 42:113552-113552, 2023 Cited by PubMed: 38096058DOI: 10.1016/j.celrep.2023.113552 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.9 Å) |
Structure validation
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