8UQ4
Structure of human RyR2-S2808D in the subprimed state in the presence of H2O2/NOC-12/GSH
This is a non-PDB format compatible entry.
Summary for 8UQ4
Entry DOI | 10.2210/pdb8uq4/pdb |
EMDB information | 42460 |
Descriptor | Ryanodine receptor 2, Peptidyl-prolyl cis-trans isomerase FKBP1B, ZINC ION, ... (4 entities in total) |
Functional Keywords | calcium channel, membrane protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 8 |
Total formula weight | 2312769.59 |
Authors | Miotto, M.C.,Marks, A.R. (deposition date: 2023-10-23, release date: 2023-11-15, Last modification date: 2024-10-02) |
Primary citation | Miotto, M.C.,Reiken, S.,Wronska, A.,Yuan, Q.,Dridi, H.,Liu, Y.,Weninger, G.,Tchagou, C.,Marks, A.R. Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders. Nat Commun, 15:8080-8080, 2024 Cited by PubMed: 39278969DOI: 10.1038/s41467-024-51791-y PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.64 Å) |
Structure validation
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