8UFR

Structure of human endothelial nitric oxide synthase heme domain in complex with 4-methyl-7-(4-methyl-2,3,4,5-tetrahydrobenzo[f][1,4]oxazepin-7-yl)quinolin-2-amine dihydrochloride

8UFR の概要

• エントリーDOI: 10.2210/pdb8ufr/pdb
• 分子名称: Nitric oxide synthase, endothelial, PROTOPORPHYRIN IX CONTAINING FE, 5,6,7,8-TETRAHYDROBIOPTERIN, ... (10 entities in total)
• 機能のキーワード: nitric oxide synthase inhibitor, heme enzyme, oxidoreductase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 205479.07

構造登録者

Li, H.,Poulos, T.L. (登録日: 2023-10-04, 公開日: 2024-03-13, 最終更新日: 2024-04-03)

• 主引用文献: Li, H.,Hardy, C.D.,Reidl, C.T.,Jing, Q.,Xue, F.,Cinelli, M.,Silverman, R.B.,Poulos, T.L.; Crystallographic and Computational Insights into Isoform-Selective Dynamics in Nitric Oxide Synthase.; Biochemistry, 63:788-796, 2024; PubMed: 38417024; DOI: 10.1021/acs.biochem.3c00601

実験手法