8U1Z

Crystal structure of the Fis1 cytosolic domain bound to a peptide inhibitor

Summary for 8U1Z

• Entry DOI: 10.2210/pdb8u1z/pdb
• Descriptor: Mitochondrial fission 1 protein, inhibitor peptide (3 entities in total)
• Functional Keywords: tetracopipeptide repeat protein, mitochondria, inhibitor, fission, peptide binding protein-inhibitor complex, peptide binding protein/inhibitor
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 16210.63

Authors

Nolden, K.A.,Peterson, F.C.,Hill, R.B. (deposition date: 2023-09-04, release date: 2024-09-04)

• Primary citation: Nolden, K.A.,Kakarla, M.,Egner, J.M.,Wang, J.,Harwig, M.C.,Puppala, V.K.,Hofeld, B.C.,Arnold, L.A.,Trykall, D.Z.,Peterson, F.C.,Roberts, M.L.,Jenson, D.M.,Hill, R.B.,Widlansky, M.E.; Novel Fis1 inhibiting peptide reverses microvascular endothelial dysfunction in vessels from humans with type 2 diabetes; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.85 Å)