8TZ8

Cryo-EM structure of bovine concentrative nucleoside transporter 3 in complex with Molnupiravir, condition 1, INT1-INT1-INT3 conformation

8TZ8 の概要

• エントリーDOI: 10.2210/pdb8tz8/pdb
• EMDBエントリー: 41737
• 分子名称: Sodium/nucleoside cotransporter, N-hydroxy-5'-O-(2-methylpropanoyl)cytidine, 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (3 entities in total)
• 機能のキーワード: membrane protein, transporter, nucleoside, transport protein
• 由来する生物種: Bos taurus (cattle)
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 240638.39

構造登録者

Wright, N.J.,Lee, S.-Y. (登録日: 2023-08-26, 公開日: 2024-03-13)

• 主引用文献: Wright, N.J.,Zhang, F.,Suo, Y.,Kong, L.,Yin, Y.,Fedor, J.G.,Sharma, K.,Borgnia, M.J.,Im, W.,Lee, S.Y.; Antiviral drug recognition and elevator-type transport motions of CNT3.; Nat.Chem.Biol., 2024; PubMed: 38418906; DOI: 10.1038/s41589-024-01559-8

実験手法

ELECTRON MICROSCOPY (3.19 Å)