8TTN
PHF1-Phosphomimetic Tau Filaments (Full-length, Cofactor-Free 0N4R Tau S396E, S400E, T403E, S404E)
Summary for 8TTN
Entry DOI | 10.2210/pdb8ttn/pdb |
EMDB information | 41611 |
Descriptor | Microtubule-associated protein tau (1 entity in total) |
Functional Keywords | tau, amyloid fibril, phosphomimetic, protein fibril |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 5 |
Total formula weight | 201139.86 |
Authors | El Mammeri, N.,Dregni, A.J.,Duan, P.,Hong, M. (deposition date: 2023-08-14, release date: 2024-06-26) |
Primary citation | Mammeri, N.E.,Dregni, A.J.,Duan, P.,Hong, M. Structures of AT8 and PHF1 phosphomimetic tau: Insights into the posttranslational modification code of tau aggregation. Proc.Natl.Acad.Sci.USA, 121:e2316175121-e2316175121, 2024 Cited by PubMed: 38408247DOI: 10.1073/pnas.2316175121 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.4 Å) |
Structure validation
Download full validation report