8TRR

T cell recognition of citrullinated vimentin peptide presented by HLA-DR4

8TRR の概要

• エントリーDOI: 10.2210/pdb8trr/pdb
• 分子名称: HLA class II histocompatibility antigen, DR alpha chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DRB1 beta chain, ... (11 entities in total)
• 機能のキーワード: immune receptor complex, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 194488.40

構造登録者

Loh, T.J.,Lim, J.J.,Reid, H.H.,Rossjohn, J. (登録日: 2023-08-10, 公開日: 2024-07-31, 最終更新日: 2024-08-07)

• 主引用文献: Loh, T.J.,Lim, J.J.,Jones, C.M.,Dao, H.T.,Tran, M.T.,Baker, D.G.,La Gruta, N.L.,Reid, H.H.,Rossjohn, J.; The molecular basis underlying T cell specificity towards citrullinated epitopes presented by HLA-DR4.; Nat Commun, 15:6201-6201, 2024; PubMed: 39043656; DOI: 10.1038/s41467-024-50511-w

実験手法

X-RAY DIFFRACTION (2.65 Å)