8TRD

mGluR3 class 1 in the presence of the antagonist LY 341495

Summary for 8TRD

• Entry DOI: 10.2210/pdb8trd/pdb
• EMDB information: 41578
• Descriptor: Metabotropic glutamate receptor 3, 2-[(1S,2S)-2-carboxycyclopropyl]-3-(9H-xanthen-9-yl)-D-alanine (2 entities in total)
• Functional Keywords: gpcr, synaptic protein, membrane protein
• Biological source: Rattus norvegicus (Norway rat)
• Total number of polymer chains: 2
• Total formula weight: 207029.85

Authors

Strauss, A.,Levitz, J. (deposition date: 2023-08-09, release date: 2024-07-31, Last modification date: 2024-08-14)

• Primary citation: Strauss, A.,Gonzalez-Hernandez, A.J.,Lee, J.,Abreu, N.,Selvakumar, P.,Salas-Estrada, L.,Kristt, M.,Arefin, A.,Huynh, K.,Marx, D.C.,Gilliland, K.,Melancon, B.J.,Filizola, M.,Meyerson, J.,Levitz, J.; Structural basis of positive allosteric modulation of metabotropic glutamate receptor activation and internalization.; Nat Commun, 15:6498-6498, 2024; PubMed: 39090128; DOI: 10.1038/s41467-024-50548-x

Experimental method

ELECTRON MICROSCOPY (3.4 Å)