8TO6

Escherichia coli RNA polymerase unwinding intermediate (I1d) at the lambda PR promoter

Summary for 8TO6

Entry DOI	10.2210/pdb8to6/pdb
EMDB information	41437
Descriptor	DNA-directed RNA polymerase subunit alpha, ZINC ION, DNA-directed RNA polymerase subunit beta, ... (10 entities in total)
Functional Keywords	dna-dependent rna polymerase, transcription, intermediate, dna promoter, dna unwinding, transcription-dna complex, transcription/dna
Biological source	Escherichia coli (strain K12) More
Total number of polymer chains	9
Total formula weight	562540.82
Authors	Darst, S.A.,Saecker, R.M.,Mueller, A.U. (deposition date: 2023-08-02, release date: 2024-07-03, Last modification date: 2024-07-17)
Primary citation	Saecker, R.M.,Mueller, A.U.,Malone, B.,Chen, J.,Budell, W.C.,Dandey, V.P.,Maruthi, K.,Mendez, J.H.,Molina, N.,Eng, E.T.,Yen, L.Y.,Potter, C.S.,Carragher, B.,Darst, S.A. Early intermediates in bacterial RNA polymerase promoter melting visualized by time-resolved cryo-electron microscopy. Nat.Struct.Mol.Biol., 2024 Cited by PubMed: 38951624 DOI: 10.1038/s41594-024-01349-9 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.9 Å)

Structure validation