8TNN

Crystal structure of Epstein-Barr virus gH/gL/gp42 in complex with gp42 antibody A10

Summary for 8TNN

• Entry DOI: 10.2210/pdb8tnn/pdb
• Descriptor: Envelope glycoprotein H, Envelope glycoprotein L, Glycoprotein 42, ... (7 entities in total)
• Functional Keywords: viral protein, antibody, immune system
• Biological source: Human herpesvirus 4 strain B95-8 (Epstein-Barr virus); More
• Total number of polymer chains: 10
• Total formula weight: 312859.45

Authors

Bu, W.,Kumar, A.,Board, N.,Kim, J.,Dowdell, K.,Zhang, S.,Lei, Y.,Hostal, A.,Krogmann, T.,Wang, Y.,Pittaluga, S.,Marcotrigiano, J.,Cohen, J.I. (deposition date: 2023-08-02, release date: 2024-03-27, Last modification date: 2024-05-22)

• Primary citation: Bu, W.,Kumar, A.,Board, N.L.,Kim, J.,Dowdell, K.,Zhang, S.,Lei, Y.,Hostal, A.,Krogmann, T.,Wang, Y.,Pittaluga, S.,Marcotrigiano, J.,Cohen, J.I.; Epstein-Barr virus gp42 antibodies reveal sites of vulnerability for receptor binding and fusion to B cells.; Immunity, 57:559-573.e6, 2024; PubMed: 38479361; DOI: 10.1016/j.immuni.2024.02.008

Experimental method

X-RAY DIFFRACTION (3.36 Å)