8TMA

Antibody N3-1 bound to RBD in the up conformation

8TMA の概要

• エントリーDOI: 10.2210/pdb8tma/pdb
• EMDBエントリー: 41382
• 分子名称: Spike glycoprotein, N3-1 Fab heavy chain, N3-1 Fab light chain (3 entities in total)
• 機能のキーワード: sars-cov-2 spike, neutralizing antibody, rbd-directed antibody, quaternary epitope, viral protein, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 168711.48

構造登録者

Hsieh, C.-L.,McLellan, J.S. (登録日: 2023-07-29, 公開日: 2024-01-17)

• 主引用文献: Goike, J.,Hsieh, C.L.,Horton, A.P.,Gardner, E.C.,Zhou, L.,Bartzoka, F.,Wang, N.,Javanmardi, K.,Herbert, A.,Abbassi, S.,Xie, X.,Xia, H.,Shi, P.Y.,Renberg, R.,Segall-Shapiro, T.H.,Terrace, C.I.,Wu, W.,Shroff, R.,Byrom, M.,Ellington, A.D.,Marcotte, E.M.,Musser, J.M.,Kuchipudi, S.V.,Kapur, V.,Georgiou, G.,Weaver, S.C.,Dye, J.M.,Boutz, D.R.,McLellan, J.S.,Gollihar, J.D.; SARS-COV-2 Omicron variants conformationally escape a rare quaternary antibody binding mode.; Commun Biol, 6:1250-1250, 2023; PubMed: 38082099; DOI: 10.1038/s42003-023-05649-6

実験手法

ELECTRON MICROSCOPY (3.2 Å)