8TLQ

Cryo-EM structure of the Rev1-Polzeta-DNA-dCTP complex

8TLQ の概要

• エントリーDOI: 10.2210/pdb8tlq/pdb
• EMDBエントリー: 41371
• 分子名称: DNA polymerase zeta catalytic subunit, DNA polymerase zeta processivity subunit, DNA polymerase delta small subunit, ... (10 entities in total)
• 機能のキーワード: dna repair, dna replication, translesion dna synthesis, dna polymerase, dna binding protein, dna binding protein-dna complex, dna binding protein/dna
• 由来する生物種: Saccharomyces cerevisiae (brewer's yeast); 詳細
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 462757.89

構造登録者

Malik, R.,Aggarwal, A.K. (登録日: 2023-07-27, 公開日: 2024-05-15, 最終更新日: 2024-05-22)

• 主引用文献: Malik, R.,Johnson, R.E.,Ubarretxena-Belandia, I.,Prakash, L.,Prakash, S.,Aggarwal, A.K.; Cryo-EM structure of the Rev1-Pol zeta holocomplex reveals the mechanism of their cooperativity in translesion DNA synthesis.; Nat.Struct.Mol.Biol., 2024; PubMed: 38720088; DOI: 10.1038/s41594-024-01302-w

実験手法

ELECTRON MICROSCOPY (3.53 Å)