8TLL
CDCA7 (Mouse) Binds Non-B-form 26-mer DNA oligo
Summary for 8TLL
Entry DOI | 10.2210/pdb8tll/pdb |
Descriptor | Cell division cycle-associated protein 7, DNA (26-MER), 1,2-ETHANEDIOL, ... (7 entities in total) |
Functional Keywords | protein-dna complex, dna binding protein, zinc fingers, chromatin architecture, dna binding protein-dna complex, dna binding protein/dna |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 4 |
Total formula weight | 49468.80 |
Authors | Horton, J.R.,Ren, R.,Cheng, X. (deposition date: 2023-07-26, release date: 2024-08-21, Last modification date: 2024-10-16) |
Primary citation | Hardikar, S.,Ren, R.,Ying, Z.,Zhou, J.,Horton, J.R.,Bramble, M.D.,Liu, B.,Lu, Y.,Liu, B.,Coletta, L.D.,Shen, J.,Dan, J.,Zhang, X.,Cheng, X.,Chen, T. The ICF syndrome protein CDCA7 harbors a unique DNA binding domain that recognizes a CpG dyad in the context of a non-B DNA. Sci Adv, 10:eadr0036-eadr0036, 2024 Cited by PubMed: 39178265DOI: 10.1126/sciadv.adr0036 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.58 Å) |
Structure validation
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