8TK5

HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE (VHR) complexed with HEPES

8TK5 の概要

• エントリーDOI: 10.2210/pdb8tk5/pdb
• 分子名称: Dual specificity protein phosphatase 3, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, TETRAETHYLENE GLYCOL, ... (6 entities in total)
• 機能のキーワード: protein dual-specificity phosphatase, vhr, hydrolase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 41819.51

構造登録者

Aleshin, A.E.,Wu, J.,Lambert, L.J.,Cosford, N.D.P.,Tautz, L. (登録日: 2023-07-25, 公開日: 2024-08-14)

• 主引用文献: Wu, J.,Aleshin, A.E.,Lambert, L.J.,Cosford, N.D.P.,Tautz, L.; Fragment Screening Platform and Discovery of Novel Fragment Binders of the VHR Phosphatase, a Drug Target for Sepsis and Septic Shock; To Be Published,

実験手法

X-RAY DIFFRACTION (1.9 Å)