8TIV

Isoreticular, interpenetrating co-crystal of Replication Initiator Protein REPE54 and symmetrical expanded duplex (31mer) containing the cognate REPE54 sequence and an additional G-C rich sequence with blunt ends and 5' terminal phosphates and crosslinked with EDC.

8TIV の概要

• エントリーDOI: 10.2210/pdb8tiv/pdb
• 関連するPDBエントリー: 7u6k
• 分子名称: DNA (5'-D(A*CP*CP*CP*GP*GP*AP*CP*CP*TP*GP*TP*GP*AP*CP*AP*AP*AP*TP*TP*GP*CP*CP*CP*TP*CP*AP*GP*AP*CP*GP*G)-3')|, DNA (5'-D(A*CP*CP*GP*TP*CP*TP*GP*AP*GP*GP*GP*CP*AP*AP*TP*TP*TP*GP*TP*CP*AP*CP*AP*GP*GP*TP*CP*CP*GP*GP*G)-3'), Replication initiation protein, ... (4 entities in total)
• 機能のキーワード: replication initiator repe complex co-crystal, dna binding protein-dna complex, dna binding protein, dna binding protein/dna
• 由来する生物種: Escherichia coli K-12; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 50468.02

構造登録者

Orun, A.R.,Shields, E.T.,Shrestha, R.,Slaughter, C.K.,Snow, C.D. (登録日: 2023-07-20, 公開日: 2023-08-02, 最終更新日: 2024-08-14)

• 主引用文献: Orun, A.R.,Slaughter, C.K.,Shields, E.T.,Vajapayajula, A.,Jones, S.,Shrestha, R.,Snow, C.D.; Tuning chemical DNA ligation within DNA crystals and protein-DNA co-crystals; Acs Nanosci Au, 2024; DOI: 10.1021/acsnanoscienceau.4c00013

実験手法

X-RAY DIFFRACTION (3.35 Å)