8TGW

Cryo-EM structure of 1059 SOSIP trimer purified via Galanthus nivalis lectin chromatography

Summary for 8TGW

Entry DOI	10.2210/pdb8tgw/pdb
EMDB information	41246
Descriptor	1059 SOSIP Surface protein gp120, 1059 SOSIP Transmembrane protein gp41, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywords	hiv-1, glycoprotein, lectin, trimer, viral protein
Biological source	Human immunodeficiency virus 1 More
Total number of polymer chains	6
Total formula weight	242491.96
Authors	Parsons, R.J.,Pothula, K.,Acharya, P. (deposition date: 2023-07-13, release date: 2024-08-28, Last modification date: 2024-09-04)
Primary citation	Parthasarathy, D.,Pothula, K.R.,Ratnapriya, S.,Cervera Benet, H.,Parsons, R.,Huang, X.,Sammour, S.,Janowska, K.,Harris, M.,Sodroski, J.,Acharya, P.,Herschhorn, A. Conformational flexibility of HIV-1 envelope glycoproteins modulates transmitted/founder sensitivity to broadly neutralizing antibodies. Nat Commun, 15:7334-7334, 2024 Cited by PubMed: 39187497 DOI: 10.1038/s41467-024-51656-4 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.6 Å)

Structure validation