8TG2

The crystal structure of the post-reactive state of UDP-sugar pyrophosphorylase from Leishmania major in complex with products UDP-Glucose and PPi

Summary for 8TG2

• Entry DOI: 10.2210/pdb8tg2/pdb
• Descriptor: UTP-monosaccharide-1-phosphate uridylyltransferase, URIDINE-5'-DIPHOSPHATE-GLUCOSE, PYROPHOSPHATE 2-, ... (4 entities in total)
• Functional Keywords: carbohydrate biosynthesis, nucleotidyltransferase, catalysis, molecular mechanism, sugar binding protein
• Biological source: Leishmania major
• Total number of polymer chains: 1
• Total formula weight: 67854.10

Authors

Prakash, O.,Fuehring, J.I.,Baruch, P.,Routier, F.H.,Fedorov, R. (deposition date: 2023-07-12, release date: 2025-02-12)

• Primary citation: Prakash, O.,Fuehring, J.I.,Baruch, P.,Routier, F.H.,Fedorov, R.; The post-reactive state structures of Leishmania major UDP-sugar pyrophosphorylase provide insights into the product release mechanism; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.4 Å)