8TF4
Wildtype rabbit TRPV5 into nanodiscs in the presence of PI(4,5)P2 and econazole
Summary for 8TF4
Entry DOI | 10.2210/pdb8tf4/pdb |
EMDB information | 41219 |
Descriptor | Transient receptor potential cation channel subfamily V member 5, ERGOSTEROL, 1-PALMITOYL-2-LINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... (4 entities in total) |
Functional Keywords | trpv5, trp channel, pi(4, 5)p2, econazole, membrane protein |
Biological source | Oryctolagus cuniculus (rabbit) |
Total number of polymer chains | 4 |
Total formula weight | 345902.74 |
Authors | De Jesus-Perez, J.J.,Fluck, E.C.,Moiseenkova-Bell, V.Y. (deposition date: 2023-07-07, release date: 2024-01-10, Last modification date: 2024-02-14) |
Primary citation | De Jesus-Perez, J.J.,Gabrielle, M.,Raheem, S.,Fluck, E.C.,Rohacs, T.,Moiseenkova-Bell, V.Y. Structural mechanism of TRPV5 inhibition by econazole. Structure, 32:148-156.e5, 2024 Cited by PubMed: 38141613DOI: 10.1016/j.str.2023.11.012 PDB entries with the same primary citation |
Experimental method |
Structure validation
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