8TCC

GTP Cyclohydrolase-IB with dehydrocostus lactone

This is a non-PDB format compatible entry.

Summary for 8TCC

• Entry DOI: 10.2210/pdb8tcc/pdb
• Related: 8G6C 8G8V
• Descriptor: GTP cyclohydrolase FolE2, MANGANESE (II) ION, 1,2-ETHANEDIOL, ... (6 entities in total)
• Functional Keywords: cyclohydrolase, gtp, dehydrocostus lactone, fole2, hydrolase-inhibitor complex, hydrolase/inhibitor
• Biological source: Burkholderia pseudomallei
• Total number of polymer chains: 4
• Total formula weight: 136201.45

Authors

McWhorter, K.L.,Amaya Lopez, C.Y.,Davis, K.M. (deposition date: 2023-06-30, release date: 2024-07-03)

• Primary citation: Zhang, Y.,McWhorter, K.L.,Rosen, P.,Klaus, J.,Gallant, E.,Amaya Lopez, C.Y.,Jhunjhunwala, R.,Chandler, J.,Davis, K.M.,Seyedsayamdost, M.R.; Combatting melioidosis with chemical synthetic lethality; To be published,

Experimental method

X-RAY DIFFRACTION (3.1 Å)