8TBR

Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor MAM758

8TBR の概要

• エントリーDOI: 10.2210/pdb8tbr/pdb
• 分子名称: Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, 3-(2-{3-[(2,4-diamino-6-phenylpyrimidin-5-yl)oxy]propoxy}phenyl)propanoic acid, ... (4 entities in total)
• 機能のキーワード: ssgcid, structural genomics, seattle structural genomics center for infectious disease, dihydrofolate reductase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase, oxidoreductase-inhibitor complex, oxidoreductase/inhibitor
• 由来する生物種: Mycobacterium ulcerans
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 20187.47

構造登録者

Seattle Structural Genomics Center for Infectious Disease,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2023-06-29, 公開日: 2024-08-28)

• 主引用文献: Woodward, E.L.,Lovell, S.,Mian, M.R.,Seibold, S.; Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor MAM758; To be published,

実験手法

X-RAY DIFFRACTION (1.75 Å)