8TBP

HLA-DRB1*15:01 in complex with smith antigen

Summary for 8TBP

• Entry DOI: 10.2210/pdb8tbp/pdb
• Descriptor: HLA class II histocompatibility antigen, DR alpha chain, HLA class II histocompatibility antigen, DRB1 beta chain, Small nuclear ribonucleoprotein-associated protein N peptide, ... (5 entities in total)
• Functional Keywords: human leukocyte antigen, hla, major histocompatibility complex, mhc, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 90241.45

Authors

Ting, Y.T.,Broury, A.,Ooi, J. (deposition date: 2023-06-29, release date: 2024-02-21)

• Primary citation: Eggenhuizen, P.J.,Cheong, R.M.Y.,Lo, C.,Chang, J.,Ng, B.H.,Ting, Y.T.,Monk, J.A.,Loh, K.L.,Broury, A.,Tay, E.S.V.,Shen, C.,Zhong, Y.,Lim, S.,Chung, J.X.,Kandane-Rathnayake, R.,Koelmeyer, R.,Hoi, A.,Chaudhry, A.,Manzanillo, P.,Snelgrove, S.L.,Morand, E.F.,Ooi, J.D.; Smith-specific regulatory T cells halt the progression of lupus nephritis.; Nat Commun, 15:899-899, 2024; PubMed: 38321013; DOI: 10.1038/s41467-024-45056-x

Experimental method

X-RAY DIFFRACTION (3.1262111426 Å)